Laboratory of the pharmaco-technological research is equipped with modern devices and equipment:
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Device for determining the particle size distribution and fractional composition of herbal raw materials, powders and granules. It consists of a set of 15 sieves with different diameters of mesh (according to Pharmacopoeia) and a shaker to control the frequency and duration of oscillations. It is used to determine the optimal size of herbal raw materials at the extraction, as well as the choice of granulation methods in the development of the composition and technology of solid dosage forms.
The battery of percolators with automatic circulation of the extractant is used to obtain extracts by various methods, as well as to study the dependence of the degree of extraction of biologically active substances on the speed of the extractant, duration of extraction, multiplicity and type of extractant.
Water bath VB-10 to study the effect of temperature on the degree of extraction of biologically active substances in a study on the development of drugs based on herbal and animal raw materials.
Vacuum drying chamber for the study of drying modes in the development of composition and technology:
1. soft extracts,
2. dry extracts,
3. solid dosage forms:
granules,
hard capsules,
tablets.
Friability tester Dual Drum Unit
Device for testing the resistance of tablets to crushing Tablet Hardness Tester EH-01P
Devices for studying the disintegration of Bathless Disintegration Tester (in the development of the composition and technology of tablets and granules) and dissolution of tablets and capsules 6 Stations Dissolution Tester, Electrolab (to study the bioavailability, bioequivalence, dependence of API release on the composition and technology of the drug).
Device for studying the flowability of powders and granules in substantiating the composition and technology of solid dosage forms.
Hydraulic press PM 15 Comecta, to study the force of ejection of tablets, selection of the size of the die and punches, the average weight of tablets, the effect of compression pressure on the abrasion of tablets and their disintegration and dissolution, as well as resistance to crushing tablets.
Automatic tablet press TDP-1.5 T to study the effect of the process of compressing and filling the die on the mass uniformity of tablets, their average weight, appearance and strength of tablets, the process of releasing API and bioavailability.
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